Stems cells can help pets, too

The Argus
Posted: 12/08/2008 05:25:54 PM PST


Millions of dogs suffer the aches and discomfort of arthritis. Millions more may be hurting without any obvious signs.
Now, a new science, using cells derived from the pet's own fat, may bring relief to many painful pooches.
When your pet has arthritis, you can almost feel the pain he is suffering. You watch as he struggles to rise from his bed, cringe as he slowly ascends the stairs, and can even hear the creaks and groans as he stretches out before his morning walk.
More than 15 million dogs in North America suffer some form of degenerative joint disease, better known as arthritis. Unfortunately, many dog owners are unaware of the pain their pet is experiencing, chalking up the slow movement to the effects of "old age."
Some dogs may receive daily doses of pain relievers and oral joint care supplements. Still others might find their way to physical therapy or rehabilitation. Some lucky pets even get ramps built in their homes, sparing them the need to climb the dreaded stairs.
But for some, these options are not enough to relieve the pain.
Sadly, many owners decide to euthanize their faithful companion because of the severity of the pain or the continued high cost of treatment.
But a potentially helpful treatment may be on the horizon — stem cell therapy.
Recently, a company developed a therapy to treat arthritis in dogs using the pet's own fat tissue.
Stem cells are precursor cells that have the potential to develop into a variety of specialized cell types.
Most people may equate this technology with the controversial use of embryonic stem cells. But this new technology uses adult stem cells derived from the fat of the pet. Since they are the pet's own cells, there is no ethical debate.
Recently, a detailed study on the use of fat-derived stem cells in dogs showed that animals receiving the treatment demonstrated a significant improvement in lameness when compared to dogs in the control group. This news has excited scientists and pet owners alike, and has many asking their veterinarians about the potential for a real world application.
All of this seems pretty miraculous and for some pets, the results are truly nothing short of a lifesaving miracle.
Some veterinarians are skeptical, however, and would like to see more controlled studies. It also is important to note several obstacles may stand in the way of your pet's pain relief.
First, not all pets are considered good candidates for this therapy.
Since anesthesia is involved in both the harvesting step and the reintroduction of the cells, this may not be ideal for patients at increased risk for anesthetics.
Additionally, according to Dr. Bob Harman, any dog with serious systemic disease, such as cancer, might not benefit from these treatments.
Next, as this therapy is only available through specially trained veterinarians, finding a credentialed doctor may take a little time.
And even though we have great feedback from owners, this is not a one shot therapy. Some pets need to return regularly for follow-up treatments. Scientists report that overexertion after treatment seems to lessen the benefits of the treatment, often leading to another trip to the veterinarian.
Finally, cost will certainly come into play as owners and veterinarians discuss this option.
Arthritis can be painful and even debilitating in any dog.
If you suspect your dog suffers from this disease, talk with your veterinarian about testing to confirm arthritis and then discuss the many treatment options.
Veterinarians will recommend a multimodal approach, combining appropriate medications, controlled exercise, weight loss, and environmental changes to make your dog's life easier.
In some cases, new technology, like stem cell therapy, might be beneficial.